Momwe mungatengere mimba mwachangu pa metformin? .
Madokotala azachipatala amagwiritsa ntchito metformin ngati gawo la chithandizo kuti atenge mimba; tikukuwuzani momwe mungachitire:
Metformin kutenga pakati
Amayi omwe ali nawo insulin kukana akhoza kukhala osiyanasiyana mavuto azimayi , kuphatikiza kuvuta kutenga pakati. Chifukwa chake, akatswiri azachipatala amasinkhasinkha metformin kuthandiza mkazi kuti athe kupewa kukana kwa insulin motero kuti azikhala ndi msambo wokwanira ndikukhala ndi pakati.
Metformin sikuti ndimatenda oterewa , koma amathandizira kuwongolera kusamba kwa amayi omwe akhudzidwa ndi insulin kukana motero kukwaniritsa mimba mosavuta . Komanso, ngati mayiyo azilimbana ndi insulin, samangokhala ndi pakati komanso amachepetsa chiopsezo chotaya mwana m'miyezi yotsatira ya mimba.
Mayiwo atakwanitsa kuthana ndi vuto la mahomoni, akuwonetsa a Internist Doctor José Víctor Manuel Rincón Ponce, waku Mexico Social Security Institute, mayendedwe ake a msambo nawonso amapangidwanso pafupipafupi, motero zidzakhala zosavuta kupanga malo abwino oti thupi lake khalani ndi pakati ndikukhala ndi pakati mokwanira.
Kutenga pakati ndikudwala matenda a polycystic ovary
Matenda a Polycystic ovary, matenda omwe amadziwika ndi kusakhazikika kwamphamvu, kusintha kwama mahomoni, komanso mawonekedwe a ma cysts angapo m'mimba mwake, amakhudza pafupifupi 8% ya akazi. Zomwe zimayambitsa matendawa ndizokayikirabe, ndipo matenda ndi chithandizo chakambidwa kale.
Chodziwika ndikuti ichi ndi chimodzi mwazifukwa zazikulu zakubala kwa amayi, komwe mungawonjezere zovuta zamagetsi, monga kunenepa kwambiri kapena kukana kwa insulin.
Kafukufuku wopangidwa ndi gulu la ofufuza ochokera kumayunivesite osiyanasiyana aku America, kuti atsimikizire zotsatira za maphunziro ang'onoang'ono pa Njira yabwino yothandizira osabereka kwa amayi omwe ali ndi matenda a polycystic ovarian , ndipo yomwe yasindikizidwa mu The New magazine England Journal of Medicine, imafotokoza kuti mankhwala akale amagwiritsira ntchito kuyambitsa mazira chifukwa cha zochita zake pa mahomoni opatsa mphamvu, clomiphene citrate, ndiyo njira yabwino kwambiri kwa azimayi omwe ali ndi vutoli kuti atenge mimba , ndi mankhwala osavuta, otchipa, otetezeka komanso othandiza.
Pazomwe adagwiritsa ntchito posachedwa anali metformin, mankhwala omwe amagwiritsidwa ntchito pochizira matenda amtundu wa 2, omwe popititsa patsogolo shuga ndi kunenepa kwambiri amavomereza kutenga pakati. Kafukufukuyu adachitika ndi azimayi 626 osabereka chifukwa cha matendawa ndipo adawagawa m'magulu atatu, gulu limodzi lidalandira mankhwala ochepetsa matenda ashuga (metformin yotulutsidwa), ina inducer ya ovulation (clomiphene citrate) ndipo wachitatu adalandira kuphatikiza mankhwala onsewa . Chithandizocho ndikutsata kumatenga masabata makumi atatu kapena atakwanitsa kutenga mimba.
Pamapeto pa phunziroli, azimayi omwe adalandira clomiphene adawonetsa kubadwa katatu kuposa gulu la metformin; Kuphatikiza apo, akalewo adakhalanso ndi mimba zambiri.
Omwe adagwiritsa ntchito mankhwala onsewa adawonetsa kuchuluka kwa ovulation kuposa ena onse, koma kubadwa sikunakwaniritsidwe, ngakhale kumafanana ndi pakati pambiri ndi gulu lomwe lidalandila ovulation inducer.
Kafukufuku wam'mbuyomu adanenanso zosiyana ndi izi, koma zotsatira zake sizinafufuzidwe pobadwa, koma mu kuchuluka kwa ovulation, chomwe sicholakalaka cha amayi omwe ali ndi vutoli.
Zolemba:
Zolemba Penyani Zambiri
- Barbieri RL, ndi al. (2017). Metformin yothandizira polycystic ovary syndrome.
uptodate.com/contents/metformin-for-treatment-of-the-polycystic-ovary-syndrome - Dziperekeni ku zisankho zabwino zothandiza kupewa zolepheretsa kubadwa. (2017).
cdc.gov/ncbddd/birthdefects/prevention.html - Kulimbana ndi DS, et al. (2011). Mankhwala a Metformin panthawi yoyembekezera. KODI:
doi.org/10.2337/dc11-1153 - Mapiritsi a Glucophage (metformin hydrochloride); Glucophage XR (metformin hydrochloride) mapiritsi otulutsa. (2017).
accessthata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf - Ogwira Ntchito Pachipatala cha Mayo. (2017). Gestational matenda ashuga.
mayoclinic.org/diseases-conditions/gestational-diabetes/basics/risk-factors/con-20014854
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