Tribedoce ili ndi vitamini B1 (thiamine hydrochloride) , vitamini B12 (hydroxocobalamin) , vitamini B6 (pyridoxine hydrochloride) . Zimapindulitsa chiwindi komanso dongosolo lamanjenje. Kuyambitsa kutseketsa magazi m'magazi akulu kumayambitsa kuchuluka kwa ntchito ya thromboplastin ndi prothrombin.
Pharmacological kanthu
Tribedoce) amatanthauza gulu la mavitamini osungunuka m'madzi. Ili ndi zochitika zambiri zachilengedwe. Tribedoce (vitamini B12 (hydroxocobalamin)) imafunika kuti magazi azikhala ndi hematopoiesis (amalimbikitsa kusasitsa maselo ofiira).
Nawo njira ya transmethylation, mayendedwe hydrogen, synthesis wa methionine, zidulo nucleic, choline, creatine. Amathandizira kudzikundikira kwama erythrocyte azinthu zopanga magulu a sulfhydryl.
Pharmacokinetics
Pambuyo poyendetsa pakamwa, Tribedoce (vitamini B12 (hydroxocobalamin)) imayamwa kuchokera m'mimba. Zimapukusidwa mu zimakhala, kukhala mawonekedwe a coenzyme - adenosylcobalamin, omwe ndi mtundu wa cyanocobalamin. Kutulutsidwa mu bile ndi mkodzo.
Chifukwa chiyani Tribedoce) amalembedwa?
Kuchepa kwa magazi chifukwa chakuchepa kwa B12; mankhwala zovuta chitsulo ndi post-hemorrhagic magazi m'thupi; kuchepa magazi m'thupi chifukwa cha poizoni ndi mankhwala; matenda a chiwindi (hepatitis, cirrhosis); matenda a myelosis; polyneuritis, radiculitis, neuralgia, amyotrophic lateral sclerosis; khanda lofooka laubongo, Down syndrome, zotumphukira zamitsempha; matenda a khungu (psoriasis, photodermatosis, dermatitis herpetiformis, neurodermatitis); kupewa ndi kuchiza matenda a Tribedoce (vitamini B12 (hydroxocobalamin)) kuperewera (kuphatikiza kugwiritsa ntchito biguanide, PASA, vitamini C pamlingo waukulu); Matenda a radiation
Mlingo ndi makonzedwe
Tribedoce) imagwiritsidwa ntchito ngati jakisoni wa SC, IV, IM, intralumbar ndi m'kamwa. Ndi kuchepa kwa magazi komwe kumakhudzana ndi kuchepa kwa Tribedoce (vitamini B12 (hydroxocobalamin)) imayambitsidwa pa 100-200 mcg m'masiku awiri.
Kuchepa kwa magazi ndi zizindikilo za funicular myelosis ndi megalocytic kuchepa kwa magazi ndi matenda a dongosolo lamanjenje: Ma micrograms 400-500 m'masiku 7 oyamba patsiku, kenako nthawi 1 masiku 5-7.
Mu nthawi ya chikhululukiro pakalibe zochitika zokonza mlingo wa funicular myelosis - 100 mcg kawiri pa mwezi, pamaso pa matenda amitsempha - mpaka 200-400 mcg 2-4 pa mwezi.
Mu pachimake pambuyo hemorrhagic magazi m'thupi ndi magazi m'thupi chitsulo pa 30-100 mcg 2-3 pa sabata. Pamene aplastic magazi m'thupi (makamaka ana) - 100 micrograms isanachitike kusintha kwachipatala.
Pamene zakudya m'thupi makanda ndi makanda msanga - 30 mcg / tsiku kwa masiku 15.
Matenda apakati komanso ozungulira amanjenje ndi matenda amitsempha omwe ali ndi matenda opweteka amathandizidwa pakuwonjezera kuchuluka - 200-500 mcg, ndikusintha kwa boma - 100 mcg / tsiku.
Njira yothandizira Tribedoce (vitamini B12 (hydroxocobalamin)) ndi milungu iwiri. Mu zotupa zowopsa za zotumphukira zamanjenje: pa 200-400 mcg tsiku lililonse kwa masiku 40-45.
Pamene matenda a chiwindi ndi matenda enaake: 30-60 mcg / tsiku kapena 100 mg tsiku lililonse kwa masiku 25-40.
Dystrophy mwa ana aang'ono, Down syndrome ndi ubongo wa ziwalo: pa 15-30 mcg tsiku lililonse.
Pamene funicular myelosis, amyotrophic lateral sclerosis imatha kupezedwa mumtsinje wa msana pa 15-30 mcg, ndikuwonjezera pang'onopang'ono kuchuluka kwa ma 200-250 micrograms.
Mu matenda a radiation, matenda ashuga amisala, amatuluka pa 60-100 mcg tsiku kwa masiku 20-30.
Pakuchepa kwa Tribedoce (Vitamin B12 (Hydroxocobalamin)) yoletsa - IV kapena IM ya 1 mg 1 kamodzi pamwezi; chithandizo: IV kapena IM ya 1 mg patsiku kwamasabata 1-2, mlingo wosamalira ndi 1-2 mg IV kapena IM 1 pa sabata, mpaka 1 pamwezi. Kutalika kwa chithandizo kumatsimikizika payekha.
malonda
Fuko zotsatira khumi ndi ziwiri zoyipa, zoyipa
CNS: kawirikawiri, mkhalidwe wachisangalalo.
Mtima dongosolo: kawirikawiri - kupweteka kwa mtima, tachycardia.
Thupi lawo siligwirizana: kawirikawiri - ming'oma.
Tribedoce) zotsutsana
Thromboembolism, erythremia, erythrocytosis, kumvetsetsa kwa cyanocobalamin.
Tribedoce) panthawi yoyembekezera komanso kuyamwitsa
Cyanocobalamin itha kugwiritsidwa ntchito pa mimba molingana ndi maphikidwe.
Malangizo apadera
Pamene stenocardia ayenera kugwiritsidwa ntchito mosamala mu mlingo umodzi wa Tribedoce 100 mg. Mukamalandira chithandizo magazi ndi magazi ayenera kuundana pafupipafupi. Sizovomerezeka kulowa mu syringe yomweyo ndi thiamine ndi pyridoxine cyanocobalamin mayankho.
Fuko kulumikizana khumi ndi awiri
Mukamagwiritsa ntchito Tribedoce (Vitamini B12 (Hydroxocobalamin)) yokhala ndi njira zakulera zam'thupi zam'kamwa zimatha kutsitsa cyanocobalamin m'magazi.
Pogwiritsa ntchito mankhwala a anticonvulsant, kuyamwa kwa cyanocobalamin m'matumbo kunachepetsedwa.
Pogwiritsa ntchito Tribedoce (Vitamini B12 (Hydroxocobalamin)) ndi neomycin, aminosalicylic acid, colchicine, cimetidine, ranitidine, mankhwala a potaziyamu amachepetsa kuyamwa kwa cyanocobalamin ndi matumbo.
Cyanocobalamin imatha kukulitsa zovuta zomwe zimayambitsa thiamine.
Pamene parenteral ntchito ya chloramphenicol akhoza kuchepetsa hematopoietic zotsatira za cyanocobalamin ndi magazi m'thupi.
Kusagwirizana kwamankhwala
Zomwe zili mu molekyulu ya cobalt ion ya cyanocobalamin imathandizira kuwonongeka kwa ascorbic acid, thiamine bromide, riboflavin mu yankho.
malonda
Mankhwala ogwiritsira ntchito Tribedoce omwe ali ndi dzina komanso mankhwala ena ofanana nawo:
Chogwiritsira ntchito ndi gawo la mankhwala kapena mankhwala omwe ali ndi biologically yogwira. Gawo ili la mankhwala limayang'anira ntchito yayikulu yamankhwala yomwe cholinga chake ndi kuchiritsa kapena kuchepetsa chizindikiro kapena matenda. Magawo ena a mankhwala omwe sagwira ntchito amatchedwa excipients; Udindo wake ndikuchita ngati galimoto kapena binder. Mosiyana ndi zomwe zimagwiritsidwa ntchito, gawo lazomwe sizikugwira ntchito ndilofunika pochiritsa kapena kuchiza matendawa. Pakhoza kukhala chimodzi kapena zingapo zosakaniza mu mankhwala.
- Vitamini B1 (thiamine hydrochloride)
- Vitamini B12 (hydroxocobalamin)
- Vitamini B6 (pyridoxine hydrochloride)
Makampani opanga mitundu khumi ndi iwiri:
Makampani opanga mankhwala ndi makampani opanga mankhwala omwe amathandizira pakukonzekera mankhwala onse, kuyambira kafukufuku wakumbuyo mpaka maphunziro, mayesero azachipatala, kutulutsa mankhwala osokoneza bongo kumsika, komanso kugulitsa mankhwala osokoneza bongo.
Ofufuza ndi omwe ali ndi udindo wofufuza zasayansi komanso zoyeserera zam'mbuyomu zomwe zidapangitsa kuti apange mankhwalawa.
Mafunso omwe amapezeka pafupipafupi
Kodi ndingayendetse kapena kuyendetsa makina olemera nditatenga Tribedoce?
Kutengera zomwe Tribedoce adachita atamwa, ngati mukumva chizungulire, kuwodzera kapena chilichonse chofooka mthupi lanu, ndiye kuti Tribedoce siyabwino kuyendetsa kapena kugwiritsa ntchito makina olemera mutamwa.
Zomwe zikutanthauza kuti musayendetse kapena kugwiritsa ntchito makina olemera mutatenga kapisozi ngati kapisoziyo ali ndi vuto lachilendo mthupi lanu monga chizungulire, kugona. Monga adanenera wamankhwala, ndizowopsa kumwa zakumwa ndikumwa mankhwala, chifukwa zimawachititsa odwala kugona ndi kuopsa kwathanzi.
Dziwani za izi, makamaka mukamamwa kapisozi wa Primosa. Ndibwino kuti mufunsane ndi dokotala nthawi kuti mupeze upangiri woyenera komanso kufunsa azachipatala. Kodi Tribedoce ndi osokoneza bongo kapena chizolowezi?
Mankhwalawa sanapangidwe ndi cholinga chofuna kusokoneza bongo kapena kuzunza anzawo. Mankhwala osokoneza bongo amatchedwa zinthu zomwe boma limayang'anira. Mwachitsanzo, Ndandanda H kapena X ku India ndi Ndandanda II-V ku United States ndizoyang'anira zinthu.
Onaninso buku la malangizo a mankhwalawa momwe mungagwiritsire ntchito ndipo onetsetsani kuti si chinthu cholamulidwa. Pomaliza, kudzipatsa nokha mankhwala ndikowopsa ku thanzi lanu. Funsani dokotala wanu kuti akupatseni mankhwala oyenera, malingaliro, ndi malangizo.
Bongo
Ngati wina awonjezera bongo ndipo ali ndi zizindikilo zoopsa monga kukomoka kapena kupuma movutikira, itanani 911. Kupanda kutero, itanani malo oyang'anira poyizoni nthawi yomweyo. Nzika zaku United States zitha kuyimbira foni malo awo oletsa poizoni ku 1-800-222-1222 . Anthu aku Canada atha kuyitanitsa malo oyang'anira poizoni m'chigawo. Zizindikiro za bongo zingaphatikizepo: kugwidwa.
Zolemba
Osagawana mankhwalawa ndi ena. Kuyesa kwa Laborator ndi / kapena zamankhwala (monga kuwerengera magazi kwathunthu, kuyesa kwa impso) kuyenera kuchitidwa mukamagwiritsa ntchito mankhwalawa. Sungani maimidwe onse azachipatala ndi labotale.
Yosungirako
Funsani malangizo azogulitsazo ndi wazamadzi wanu kuti mumve zambiri. Sungani mankhwala onse osafikirika ndi ana ndi ziweto zanu, musathirire mankhwala kuchimbudzi kapena kuwatsanulira ngalande pokhapokha atalangizidwa kutero. Kutaya bwino mankhwalawa ukatha kapena osafunikanso. Funsani wamankhwala kapena kampani yakampani yotaya zinyalala.
Chodzikanira: Atumiki achita zonse zotheka kuti zidziwitso zonse zikhale zolondola, zokwanira komanso zaposachedwa. Komabe, nkhaniyi sikuyenera kugwiritsidwa ntchito m'malo mwa chidziwitso ndi chidziwitso cha akatswiri azachipatala omwe ali ndi zilolezo. Muyenera kufunsa adotolo kapena akatswiri azaumoyo musanamwe mankhwala aliwonse.
Zambiri zamankhwala zomwe zili pano zitha kusintha ndipo sizikukonzekera zochitika zonse zomwe zingagwiritsidwe ntchito, malangizo, zodzitetezera, machenjezo, kulumikizana ndi mankhwala osokoneza bongo, zovuta zina, kapena zovuta zina. Kusapezeka kwa machenjezo kapena zidziwitso zina za mankhwala enaake sikuwonetsa kuti kuphatikiza mankhwala kapena mankhwalawa ndiwotetezeka, ogwira ntchito, komanso oyenera odwala onse kapena ntchito zina zilizonse.
ZOKHUDZA
- Tsiku ndi Tsiku. ASIDI YA ASCORBIC; BIOTIN; CHOLECALCIFEROL; CYANOCOBALAMIN; DEXPANTHENOL; MAFUNSO A FOLIC; NIACINAMIDE; PYRIDOXINE; RIBOFLAVIN; THIAMINE; TOCOPHEROL ACETATE; VITAMIN A; VITAMIN K: DailyMed imapereka zodalirika zokhudzana ndi mankhwala omwe amagulitsidwa ku United States. DailyMed ndi omwe amapereka zidziwitso za ma label a FDA (maphukusi oyikapo) .. https://dailymed.nlm.nih.gov/dailyme… (yofikira pa Seputembara 17, 2018).
- Tsiku ndi Tsiku. DICLOFENAC EPOLAMINE: DailyMed imapereka chidziwitso chodalirika chokhudza mankhwala ogulitsa ku United States. DailyMed ndi omwe amapereka zidziwitso za ma label a FDA (maphukusi oyikapo) .. https://dailymed.nlm.nih.gov/dailyme… (yofikira pa Seputembara 17, 2018).
- Zamakono. diclofenac. https://pubchem.ncbi.nlm.nih.gov/com… (yofikira pa Seputembara 17, 2018).
- Zamakono. thiamine. https://pubchem.ncbi.nlm.nih.gov/com… (yofikira pa Seputembara 17, 2018).
- Zamakono. alireza. https://pubchem.ncbi.nlm.nih.gov/com… (yofikira pa September 17, 2018)
Zamkatimu
- Pharmacological kanthu
- Pharmacokinetics
- Chifukwa chiyani Tribedoce) amalembedwa?
- Mlingo ndi makonzedwe
- Fuko zotsatira khumi ndi ziwiri zoyipa, zoyipa
- Tribedoce) zotsutsana
- Tribedoce) panthawi yoyembekezera komanso kuyamwitsa
- Malangizo apadera
- Fuko kulumikizana khumi ndi awiri
- Mankhwala ogwiritsira ntchito Tribedoce omwe ali ndi dzina komanso mankhwala ena ofanana nawo:
- Makampani opanga mitundu khumi ndi iwiri:
- Mafunso omwe amapezeka pafupipafupi
- Bongo
- Zolemba
- Yosungirako
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